This repository contains high-resolution molecular maps and proteomic data characterizing the diversity of billions of individual synapses across the human brain, as pioneered by the Grant Lab at the University of Edinburgh. The dataset captures the "synaptome architecture," illustrating how the spatial distribution of diverse synapse types forms a structural logic for storing and recalling information. Utilizing advanced image analysis and computational tools, these records provide a baseline for the molecular organization of neural circuitry across different brain regions and age groups. The collection is specifically designed to facilitate research into how this architecture is remodeled by genetic mutations, aging, and neurodegenerative conditions like Alzheimer’s and schizophrenia. By integrating these synaptome maps into the EIDF ecosystem, the project aims to bridge the gap between molecular proteomics and systems-level brain function.